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The microbial mimic poly IC induces durable and protective CD4(+) T cell immunity together with a dendritic cell targeted vaccine
CD4(+) Th1 type immunity is implicated in resistance to global infectious diseases. To improve the efficacy of T cell immunity induced by human immunodeficiency virus (HIV) vaccines, we are developing a protein-based approach that directly harnesses the function of dendritic cells (DCs) in intact ly...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268178/ https://ncbi.nlm.nih.gov/pubmed/18256187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711976105 |
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