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Dendritic cell-targeted protein vaccines: a novel approach to induce T cell immunity

Current vaccines primarily work by inducing protective antibodies. However, in many infections like HIV, malaria and tuberculosis as well as cancers there remains a need for durable and protective T-cell immunity. Here, we summarize our efforts to develop a safe T-cell based protein vaccine that exp...

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Detalhes bibliográficos
Main Authors: Trumpfheller, Christine, Longhi, M. Paula, Caskey, Marina, Idoyaga, Juliana, Bozzacco, Leonia, Keler, Tibor, Schlesinger, Sarah J., Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261312/
https://ncbi.nlm.nih.gov/pubmed/22126373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2796.2011.02496.x
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