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HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine dendritic cells
Dendritic cells present exogenous proteins to MHC class I restricted CD8(+) T cells. This function does not require endogenous antigen synthesis within DC, providing the potential to elicit CD8(+) T cell responses to immune complexes, inactivated microbes, dying cells and proteins like ovalbumin. In...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933266/ https://ncbi.nlm.nih.gov/pubmed/19830741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939748 |
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