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Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8(+) T cells
To improve the efficacy of T cell–based vaccination, we pursued the principle that CD4(+) T cells provide help for functional CD8(+) T cell immunity. To do so, we administered HIV gag to mice successively as protein and DNA vaccines. To achieve strong CD4(+) T cell immunity, the protein vaccine was...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840096/ https://ncbi.nlm.nih.gov/pubmed/20160099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000621107 |
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