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The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

DNA vaccines promote an immune response by providing antigen-encoding DNA to the recipient, but the efficacy of such vaccines needs improving. Many approaches have considerable potential but currently induce relatively weak immune responses despite multiple high doses of DNA vaccine. Here, we asked...

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Detalhes bibliográficos
Main Authors: Nchinda, Godwin, Kuroiwa, Janelle, Oks, Margarita, Trumpfheller, Christine, Park, Chae Gyu, Huang, Yaoxing, Hannaman, Drew, Schlesinger, Sarah J., Mizenina, Olga, Nussenzweig, Michel C., Überla, Klaus, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263146/
https://ncbi.nlm.nih.gov/pubmed/18324335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34224
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