The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

DNA vaccines promote an immune response by providing antigen-encoding DNA to the recipient, but the efficacy of such vaccines needs improving. Many approaches have considerable potential but currently induce relatively weak immune responses despite multiple high doses of DNA vaccine. Here, we asked...

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Bibliografski detalji
Glavni autori: Nchinda, Godwin, Kuroiwa, Janelle, Oks, Margarita, Trumpfheller, Christine, Park, Chae Gyu, Huang, Yaoxing, Hannaman, Drew, Schlesinger, Sarah J., Mizenina, Olga, Nussenzweig, Michel C., Überla, Klaus, Steinman, Ralph M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2008
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263146/
https://ncbi.nlm.nih.gov/pubmed/18324335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34224
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