The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

DNA vaccines promote an immune response by providing antigen-encoding DNA to the recipient, but the efficacy of such vaccines needs improving. Many approaches have considerable potential but currently induce relatively weak immune responses despite multiple high doses of DNA vaccine. Here, we asked...

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Detaylı Bibliyografya
Asıl Yazarlar: Nchinda, Godwin, Kuroiwa, Janelle, Oks, Margarita, Trumpfheller, Christine, Park, Chae Gyu, Huang, Yaoxing, Hannaman, Drew, Schlesinger, Sarah J., Mizenina, Olga, Nussenzweig, Michel C., Überla, Klaus, Steinman, Ralph M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263146/
https://ncbi.nlm.nih.gov/pubmed/18324335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34224
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