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Treatment with a Farnesyltransferase Inhibitor Improves Survival in Mice with a Hutchinson-Gilford Progeria Syndrome Mutation
Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid syndrome characterized by multiple aging-like disease phenotypes. We recently reported that a protein farnesyltransferase inhibitor (FTI) improved several disease phenotypes in mice with a HGPS mutation (Lmna(HG/+)). Here, we investigated th...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266774/ https://ncbi.nlm.nih.gov/pubmed/18082640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2007.11.003 |
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