Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson–Gilford progeria syndrome

Hutchinson–Gilford progeria syndrome (HGPS) is an extremely rare, fatal, segmental premature aging syndrome caused by a mutation in LMNA that produces the farnesylated aberrant lamin A protein, progerin. This multisystem disorder causes failure to thrive and accelerated atherosclerosis leading to ea...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Główni autorzy: Gordon, Leslie B., Kleinman, Monica E., Miller, David T., Neuberg, Donna S., Giobbie-Hurder, Anita, Gerhard-Herman, Marie, Smoot, Leslie B., Gordon, Catherine M., Cleveland, Robert, Snyder, Brian D., Fligor, Brian, Bishop, W. Robert, Statkevich, Paul, Regen, Amy, Sonis, Andrew, Riley, Susan, Ploski, Christine, Correia, Annette, Quinn, Nicolle, Ullrich, Nicole J., Nazarian, Ara, Liang, Marilyn G., Huh, Susanna Y., Schwartzman, Armin, Kieran, Mark W.
Format: Artigo
Język:Inglês
Wydane: National Academy of Sciences 2012
Hasła przedmiotowe:
Biological Sciences
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478615/
https://ncbi.nlm.nih.gov/pubmed/23012407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202529109
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy