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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
We demonstrate a role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. In particular, transient increased expression of Sirt1 is sufficient to stimulate basal rates of autophagy. In addition, we show that Sirt1(−/−) mouse embryonic fibroblasts do not fully activate autophagy u...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265142/ https://ncbi.nlm.nih.gov/pubmed/18296641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712145105 |
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