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SIRT6 IN DNA REPAIR, METABOLISM, AND AGEING

Ageing, or increased mortality with time, coupled with physiologic decline, is a nearly universal yet poorly understood biological phenomenon. Studies in model organisms suggest that two conserved pathways modulate longevity: DNA damage repair and insulin/Igf1-like signaling. In addition, homologs o...

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Detalhes bibliográficos
Main Authors: Lombard, David B., Schwer, Bjoern, Alt, Frederick W., Mostoslavsky, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486832/
https://ncbi.nlm.nih.gov/pubmed/18226091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2796.2007.01902.x
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