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The NAD-dependent deacetylase SIRT2 regulates T cell differentiation involved in tumor immune response

Sirtuin 2 (SIRT2), an NAD+-dependent deacetylase, regulates multiple biologic and pathologic processes including mitosis, genomic integrity, cell homeostasis and tumorigenesis. However, the role of SIRT2 in the immune response to cancer remains largely elusive. In this study, we found significantly...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Jiang, Cui, Liu, Jingwei, Guo, Min, Gao, Xiaoxin, Wu, Xuan, Bai, Ning, Guo, Wendong, Li, Na, Yi, Fei, Cheng, Rong, Xu, Hongde, Zhou, Tingting, Jiang, Bo, Sun, Tao, Wei, Shi, Cao, Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545715/
https://ncbi.nlm.nih.gov/pubmed/33061819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.49735
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