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Ligand-transporter interaction in the AcrB multidrug efflux pump determined by fluorescence polarization assay

The AcrB of Escherichia coli pumps out a wide range of compounds, including most of the currently available antibiotics, and contributes significantly to the serious problem of multi-drug resistance of pathogenic bacteria. Quantitative analysis of drug efflux by this pump requires the measurement of...

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Détails bibliographiques
Auteurs principaux: Su, Chih-Chia, Nikaido, Hiroshi, Yu, Edward W.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254335/
https://ncbi.nlm.nih.gov/pubmed/17910961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.09.035
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