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Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli

Multidrug efflux transporters, especially those that belong to the resistance-nodulation-division (RND) family, often show very broad substrate specificity and play a major role both in the intrinsic antibiotic resistance and, with increased levels of expression, in the elevated resistance of Gram-n...

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Hlavní autoři: Nagano, Keiji, Nikaido, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667059/
https://ncbi.nlm.nih.gov/pubmed/19307562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901695106
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