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Vestibules Are Part of the Substrate Path in the Multidrug Efflux Transporter AcrB of Escherichia coli
The path of substrates in the multidrug efflux pump AcrB of Escherichia coli was examined by using labeling with a lipophilic substrate mimic, Bodipy FL maleimide. Four (out of eight) residues in the vestibule bound the dye, suggesting its role in substrate transport, whereas only one (out of nine)...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187200/ https://ncbi.nlm.nih.gov/pubmed/21856849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05759-11 |
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