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Ligand-transporter interaction in the AcrB multidrug efflux pump determined by fluorescence polarization assay
The AcrB of Escherichia coli pumps out a wide range of compounds, including most of the currently available antibiotics, and contributes significantly to the serious problem of multi-drug resistance of pathogenic bacteria. Quantitative analysis of drug efflux by this pump requires the measurement of...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254335/ https://ncbi.nlm.nih.gov/pubmed/17910961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.09.035 |
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