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Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid

Amyloidogenesis from soluble protein requires conformational and oligomeric assembly steps. In systems where the precursor protein is natively unfolded, such as islet amyloid polypeptide (IAPP), forces and structural changes relevant to protein unfolding are not thought to participate in the assembl...

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Hlavní autoři: Koo, Bon W., Miranker, Andrew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253339/
https://ncbi.nlm.nih.gov/pubmed/15576552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041051205
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