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Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid

Amyloidogenesis from soluble protein requires conformational and oligomeric assembly steps. In systems where the precursor protein is natively unfolded, such as islet amyloid polypeptide (IAPP), forces and structural changes relevant to protein unfolding are not thought to participate in the assembl...

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Autori principali: Koo, Bon W., Miranker, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253339/
https://ncbi.nlm.nih.gov/pubmed/15576552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041051205
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