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Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid
Amyloidogenesis from soluble protein requires conformational and oligomeric assembly steps. In systems where the precursor protein is natively unfolded, such as islet amyloid polypeptide (IAPP), forces and structural changes relevant to protein unfolding are not thought to participate in the assembl...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253339/ https://ncbi.nlm.nih.gov/pubmed/15576552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041051205 |
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