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Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid

Amyloidogenesis from soluble protein requires conformational and oligomeric assembly steps. In systems where the precursor protein is natively unfolded, such as islet amyloid polypeptide (IAPP), forces and structural changes relevant to protein unfolding are not thought to participate in the assembl...

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Detalhes bibliográficos
Main Authors: Koo, Bon W., Miranker, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253339/
https://ncbi.nlm.nih.gov/pubmed/15576552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041051205
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