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Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin
Islet amyloid polypeptide (IAPP, also known as amylin) is the major protein component of pancreatic amyloid fibers in type II diabetes and is normally cosecreted with insulin from the β-cells of the pancreas. IAPP forms amyloid fibrils rapidly at concentrations well below those found in vivo, yet pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2548354/ https://ncbi.nlm.nih.gov/pubmed/18765820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036350.108 |
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