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Molecular regulation of T-cell anergy

The activation of T cells is tightly controlled by many positive and negative regulatory processes. This fine-tuning allows productive immunity to pathogens while minimizing the risk of autoimmunity. One negative regulatory mechanism is clonal anergy, which is a hyporesponsive state that occurs when...

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Detalhes bibliográficos
Main Authors: Zheng, Yan, Zha, Yuanyuan, Gajewski, Thomas F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246614/
https://ncbi.nlm.nih.gov/pubmed/18174897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401138
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