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Molecular underpinning of B-cell anergy
A byproduct of the largely stochastic generation of a diverse B-cell specificity repertoire is production of cells that recognize autoantigens. Indeed, recent studies indicate that more than half of the primary repertoire consists of autoreactive B cells that must be silenced to prevent autoimmunity...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2968701/ https://ncbi.nlm.nih.gov/pubmed/20727040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00936.x |
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