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Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy

T cell anergy is one of the mechanisms contributing to peripheral tolerance, particularly in the context of progressively growing tumors and in tolerogenic treatments promoting allograft acceptance. We recently reported that early growth response gene 2 (Egr2) is a critical transcription factor for...

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Autori principali: Zheng, Yan, Zha, Yuanyuan, Spaapen, Robbert M., Mathew, Rebecca, Barr, Kenneth, Bendelac, Albert, Gajewski, Thomas F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646929/
https://ncbi.nlm.nih.gov/pubmed/23548837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2013.03.006
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