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Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo

T cell receptor engagement in the absence of costimulation results in a hyporesponsive state termed anergy. Understanding the transcriptional regulation of other T cell differentiation states has provided critical information regarding the biology of T cell regulation in vivo. However, the transcrip...

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Detalhes bibliográficos
Main Authors: Zheng, Yan, Zha, Yuanyuan, Driessens, Gregory, Locke, Frederick, Gajewski, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501351/
https://ncbi.nlm.nih.gov/pubmed/23129747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120342
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