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Human Innate Mycobacterium tuberculosis–Reactive αβTCR(+) Thymocytes

The control of Mycobacterium tuberculosis (Mtb) infection is heavily dependent on the adaptive Th1 cellular immune response. Paradoxically, optimal priming of the Th1 response requires activation of priming dendritic cells with Th1 cytokine IFN-γ. At present, the innate cellular mechanisms required...

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Detalhes bibliográficos
Main Authors: Gold, Marielle C, Ehlinger, Heather D, Cook, Matthew S, Smyk-Pearson, Susan K, Wille, Paul T, Ungerleider, Ross M, Lewinsohn, Deborah A, Lewinsohn, David M
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242840/
https://ncbi.nlm.nih.gov/pubmed/18282101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040039
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