Pre-TCR ligand binding impacts thymocyte development before αβTCR expression

Adaptive cellular immunity requires accurate self- vs. nonself-discrimination to protect against infections and tumorous transformations while at the same time excluding autoimmunity. This vital capability is programmed in the thymus through selection of αβT-cell receptors (αβTCRs) recognizing pepti...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Mallis, Robert J., Bai, Ke, Arthanari, Haribabu, Hussey, Rebecca E., Handley, Maris, Li, Zhenhai, Chingozha, Loice, Duke-Cohan, Jonathan S., Lu, Hang, Wang, Jia-Huai, Zhu, Cheng, Wagner, Gerhard, Reinherz, Ellis L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500245/
https://ncbi.nlm.nih.gov/pubmed/26056289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504971112
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller