Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress

Human mucosal-associated invariant T (MAIT) cells express the semi-invariant T cell receptor Vα7.2 and are restricted by the MHC-Ib molecule MR1. While MAIT cells share similarities with other innate T cells the extent to which MAIT cells are innate and their capacity to adapt is unknown. We evaluat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gold, Marielle C., Eid, Tarek, Smyk-Pearson, Sue, Eberling, Yvonne, Swarbrick, Gwendolyn M., Langley, Stephen M., Streeter, Philip R., Lewinsohn, Deborah A., Lewinsohn, David M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443511/
https://ncbi.nlm.nih.gov/pubmed/22692454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.45
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