The Molecular Signature Underlying the Thymic Migration and Maturation of TCRαβ(+)CD4(+)CD8(-) Thymocytes

BACKGROUND: After positive selection, the newly generated single positive (SP) thymocytes migrate to the thymic medulla, where they undergo negative selection to eliminate autoreactive T cells and functional maturation to acquire immune competence and egress capability. METHODOLOGY/PRINCIPAL FINDING...

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Detalhes bibliográficos
Main Authors: Teng, Fei, Zhou, Yubin, Jin, Rong, Chen, Yu, Pei, Xiaoyan, Liu, Yuanfeng, Dong, Jie, Wang, Wei, Pang, Xuewen, Qian, Xiaoping, Chen, Wei-Feng, Zhang, Yu, Ge, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192722/
https://ncbi.nlm.nih.gov/pubmed/22022412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025567
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