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The effects of sodium sulfate, glycosaminoglycans, and Congo red on the structure, stability, and amyloid formation of an immunoglobulin light-chain protein

Light-chain amyloidosis (AL) is characterized by immunoglobulin light-chain fragments aggregating into amyloid fibrils that deposit extracellularly in vital organs such as the kidney, the heart, and the liver, resulting in tissue degeneration and organ failure, leading to death. Cardiac involvement...

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Detalhes bibliográficos
Main Authors: Mclaughlin, Richard W., De Stigter, Janelle K., Sikkink, Laura A., Baden, Elizabeth M., Ramirez-Alvarado, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242560/
https://ncbi.nlm.nih.gov/pubmed/16751605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051997606
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