Immunoglobulin light chain amyloid aggregation

Light chain (AL) amyloidosis is a devastating, complex, and incurable protein misfolding disease. It is characterized by an abnormal proliferation of plasma cells (fully differentiated B cells) producing an excess of monoclonal immunoglobulin light chains that are secreted into circulation, where th...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Blancas-Mejia, Luis M., Misra, Pinaki, Dick, Christopher J., Cooper, Shawna A., Redhage, Keely R., Bergman, Michael R., Jordan, Torri L., Maar, Khansaa, Ramirez-Alvarado, Marina
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148388/
https://ncbi.nlm.nih.gov/pubmed/30087961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc04396e
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