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Mechanistic insights into the early events in the aggregation of immunoglobulin light chains

Little is known about the mechanism of amyloid assembly in immunoglobulin light chain (AL) amyloidosis, in contrast to other amyloid diseases. Early events in the aggregation pathway are especially important as these soluble species could be cytotoxic intermediates playing a critical role in the ini...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Misra, Pinaki, Blancas-Mejia, Luis. M., Ramirez-Alvarado, Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650354/
https://ncbi.nlm.nih.gov/pubmed/31287666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00311
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