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Differences in protein concentration dependence for nucleation and elongation in light chain amyloid formation
Light chain (AL) amyloidosis is a lethal disease characterized by the deposition of the immunoglobulin light chain into amyloid fibrils, resulting in organ dysfunction and failure. Amyloid fibrils have the ability to self-propagate recruiting soluble protein into the fibril by a nucleation-polymeriz...
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| Vydáno v: | Biochemistry |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5310643/ https://ncbi.nlm.nih.gov/pubmed/28074646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01043 |
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