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Differences in protein concentration dependence for nucleation and elongation in light chain amyloid formation

Light chain (AL) amyloidosis is a lethal disease characterized by the deposition of the immunoglobulin light chain into amyloid fibrils, resulting in organ dysfunction and failure. Amyloid fibrils have the ability to self-propagate recruiting soluble protein into the fibril by a nucleation-polymeriz...

詳細記述

保存先:
書誌詳細
出版年:Biochemistry
主要な著者: Blancas-Mejía, Luis M., Misra, Pinaki, Ramirez-Alvarado, Marina
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310643/
https://ncbi.nlm.nih.gov/pubmed/28074646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01043
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