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Differential Effects on Light Chain Amyloid Formation Depend on Mutations and Type of Glycosaminoglycans
Amyloid light chain (AL) amyloidosis is a protein misfolding disease where immunoglobulin light chains sample partially folded states that lead to misfolding and amyloid formation, resulting in organ dysfunction and death. In vivo, amyloid deposits are found in the extracellular space and involve a...
Gespeichert in:
| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335233/ https://ncbi.nlm.nih.gov/pubmed/25538238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615401 |
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