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Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
The Mixed Lineage Leukemia (Mll) gene is essential for embryonic hematopoietic stem cell (HSC) development but its role during adult hematopoiesis is unknown. Using an inducible knockout model, we demonstrate that Mll is essential for the maintenance of adult HSCs and progenitors, with fatal bone ma...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234224/ https://ncbi.nlm.nih.gov/pubmed/18371366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2007.05.019 |
| Etiketak: |
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