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Leukemia and Hematopoietic Stem Cells: Balancing Proliferation and Quiescence

Chromosomal translocations that disrupt transcriptional regulators are frequently involved in the etiology of leukemia. To gain an understanding of the normal and pathologic roles of these transcriptional regulators, both gain- and loss-of-function mutations have been examined in the context of stea...

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Autors principals: Jude, Craig D., Gaudet, Justin, Speck, Nancy, Ernst, Patricia
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892629/
https://ncbi.nlm.nih.gov/pubmed/18239455
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