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DNA Methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

DNA methylation is essential for development and in diverse biological processes. The DNA methyltransferase Dnmt1 maintains parental cell methylation patterns on daughter DNA strands in mitotic cells, however, the precise role of Dnmt1 in regulation of quiescent adult stem cells is not known. To exa...

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Autors principals: Trowbridge, Jennifer J., Snow, Jonathan W., Kim, Jonghwan, Orkin, Stuart H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767228/
https://ncbi.nlm.nih.gov/pubmed/19796624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.08.016
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