NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional surveillance process that eliminates mRNAs containing premature termination codons (PTCs). NMD has been hypothesized to impact on several aspects of cellular function; however, its importance in the context of a mammalian organism has not...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Weischenfeldt, Joachim, Damgaard, Inge, Bryder, David, Theilgaard-Mönch, Kim, Thoren, Lina A., Nielsen, Finn Cilius, Jacobsen, Sten Eirik W., Nerlov, Claus, Porse, Bo Torben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377192/
https://ncbi.nlm.nih.gov/pubmed/18483223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.468808
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge