Self-Renewal of Multipotent Long-Term Repopulating Hematopoietic Stem Cells Is Negatively Regulated by FAS and Tumor Necrosis Factor Receptor Activation

Multipotent self-renewing hematopoietic stem cells (HSCs) are responsible for reconstitution of all blood cell lineages. Whereas growth stimulatory cytokines have been demonstrated to promote HSC self-renewal, the potential role of negative regulators remains elusive. Receptors for tumor necrosis fa...

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Detalhes bibliográficos
Main Authors: Bryder, David, Ramsfjell, Veslemøy, Dybedal, Ingunn, Theilgaard-Mönch, Kim, Högerkorp, Carl-Magnus, Adolfsson, Jörgen, Borge, Ole Johan, Jacobsen, Sten Eirik W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193477/
https://ncbi.nlm.nih.gov/pubmed/11581316
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