Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

Whereas maintenance of hematopoietic stem cells (HSCs) is a requisite for life, uncontrolled expansion of HSCs might enhance the propensity for leukemic transformation. Accordingly, HSC numbers are tightly regulated. The identification of physical cellular HSC niches has underscored the importance o...

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Detalhes bibliográficos
Main Authors: Pronk, Cornelis J.H., Veiby, Ole Petter, Bryder, David, Jacobsen, Sten Eirik W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149225/
https://ncbi.nlm.nih.gov/pubmed/21768269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110752
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