Caricamento...
Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations
Histone H2AX is required to maintain genomic stability in cells and to suppress malignant transformation of lymphocytes in mice. H2ax(−/−)p53(−/−) mice succumb predominantly to immature αβ T-cell lymphomas with translocations, deletions, and genomic amplifications that do not involve T-cell receptor...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2008
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234053/ https://ncbi.nlm.nih.gov/pubmed/17855626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-104760 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|