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Chipping Away at γ-H2AX Foci

The mammalian histone H2AX protein functions as a dosage-dependent genomic caretaker and tumor suppressor. Phosphorylation of H2AX to form γ-H2AX in chromatin around DNA double strand breaks (DSBs) is an early event following induction of these hazardous lesions. For a decade, mechanisms that regula...

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Autors principals: Savic, Velibor, Sanborn, Keri B., Orange, Jordan S., Bassing, Craig H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879071/
https://ncbi.nlm.nih.gov/pubmed/19770593
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