Distinct Functions for Arf Guanine Nucleotide Exchange Factors at the Golgi Complex: GBF1 and BIGs Are Required for Assembly and Maintenance of the Golgi Stack and trans-Golgi Network, Respectively

We examined the relative function of the two classes of guanine nucleotide exchange factors (GEFs) for ADP-ribosylation factors that regulate recruitment of coat proteins on the Golgi complex. Complementary overexpression and RNA-based knockdown approaches established that GBF1 regulates COPI recrui...

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Autores principales: Manolea, Florin, Claude, Alejandro, Chun, Justin, Rosas, Javier, Melançon, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2008
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230590/
https://ncbi.nlm.nih.gov/pubmed/18003980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-04-0394
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