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Arf3 Is Activated Uniquely at the trans-Golgi Network by Brefeldin A-inhibited Guanine Nucleotide Exchange Factors

It is widely assumed that class I and II Arfs function interchangeably throughout the Golgi complex. However, we report here that in vivo, Arf3 displays several unexpected properties. Unlike other Golgi-localized Arfs, Arf3 associates selectively with membranes of the trans-Golgi network (TGN) in a...

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Autors principals: Manolea, Florin, Chun, Justin, Chen, David W., Clarke, Ian, Summerfeldt, Nathan, Dacks, Joel B., Melançon, Paul
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877642/
https://ncbi.nlm.nih.gov/pubmed/20357002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0016
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