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Coupling between Voltage Sensor Activation, Ca(2+) Binding and Channel Opening in Large Conductance (BK) Potassium Channels

To determine how intracellular Ca(2+) and membrane voltage regulate the gating of large conductance Ca(2+)-activated K(+) (BK) channels, we examined the steady-state and kinetic properties of mSlo1 ionic and gating currents in the presence and absence of Ca(2+) over a wide range of voltage. The acti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Horrigan, Frank T., Aldrich, Richard W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229516/
https://ncbi.nlm.nih.gov/pubmed/12198087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028605
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