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Mg(2+) Enhances Voltage Sensor/Gate Coupling in BK Channels
BK (Slo1) potassium channels are activated by millimolar intracellular Mg(2+) as well as micromolar Ca(2+) and membrane depolarization. Mg(2+) and Ca(2+) act in an approximately additive manner at different binding sites to shift the conductance–voltage (G(K)-V) relation, suggesting that these ligan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174156/ https://ncbi.nlm.nih.gov/pubmed/18166624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709877 |
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