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Mg(2+) mediates interaction between the voltage sensor and cytosolic domain to activate BK channels
The voltage-sensor domain (VSD) of voltage-dependent ion channels and enzymes is critical for cellular responses to membrane potential. The VSD can also be regulated by interaction with intracellular proteins and ligands, but how this occurs is poorly understood. Here, we show that the VSD of the BK...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084332/ https://ncbi.nlm.nih.gov/pubmed/17984060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705873104 |
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