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Activation of Slo1 BK channels by Mg(2+) coordinated between the voltage sensor and the RCK1 domains
The voltage sensor domain (VSD) and the ligand sensor (cytoplasmic domain) of BK channels synergistically control channel activities, thereby integrating electrical and chemical signals for cell function. Studies show that intracellular Mg(2+) mediates the interaction between these sensory domains t...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579968/ https://ncbi.nlm.nih.gov/pubmed/18931675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1507 |
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