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A Charged Residue in S4 Regulates Coupling among the Activation Gate, Voltage, and Ca(2+) Sensors in BK Channels

Coupling between the activation gate and sensors of physiological stimuli during ion channel activation is an important, but not well-understood, molecular process. One difficulty in studying sensor–gate coupling is to distinguish whether a structural perturbation alters the function of the sensor,...

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Detalhes bibliográficos
Main Authors: Zhang, Guohui, Yang, Huanghe, Liang, Hongwu, Yang, Junqiu, Shi, Jingyi, McFarland, Kelli, Chen, Yihan, Cui, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160767/
https://ncbi.nlm.nih.gov/pubmed/25209270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1174-14.2014
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