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Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels
Large conductance Ca(2+)-activated K(+) channels (BK channels) gate open in response to both membrane voltage and intracellular Ca(2+). The channel is formed by a central pore-gate domain (PGD), which spans the membrane, plus transmembrane voltage sensors and a cytoplasmic gating ring that acts as a...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339509/ https://ncbi.nlm.nih.gov/pubmed/28196879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611646 |
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